Bittium NeurOne™ Tesla EEG System

Bittium NeurOne™ is one of the quickest and most accurate electroencephalography (EEG) measuring devices in the world designed for research use. It is developed for the needs of medical professionals and scientists to detect simultaneously high accuracy neurophysiological signals from multiple channels without compromising data integrity.

Bittium NeurOne system enables fully synchronized group measuring of up to 30 persons simultaneously, for example in different types of psychological studies. The solution is optimized for use with transcranial magnetic stimulators (TMS-EEG), with optional possibility to use it during magnetic resonance imaging procedures (fMRI-EEG).

Bittium NeurOne system is used by many high-ranking research institutes for measuring concurrent EEG with transcranial magnetic stimulation (TMS-EEG). Bittium NeurOne real-time DigiOut functionality enables TMS stimulation at the certain moment of EEG wave, e.g. based on 10 Hz alpha frequency/phase (alpha rhythm on occipital area or mu rhythm on motor area). Based on the application, terms Brain State dependent stimulation or Closed Loop TMS stimulation are used. Dynamic range of NeurOne Tesla amplifier (±430 mV) makes Tesla-amplifier especially suitable for all EEG measurements during various stimulations.

Brain state-dependent brain stimulation with real-time electroencephalography-triggered transcranial magnetic stimulation. Maria-Ioanna Stefanou et al. Journal of Visualized Experiments, 2019.

Synchronizing the transcranial magnetic pulse with electroencephalographic recordings effectively reduces inter-trial variability of the pulse artefact. Leo Tomasevic et al. PLoS ONE, 2017.

Prefrontal Theta-Phase Synchronized Brain Stimulation With Real-Time EEG-Triggered TMS P. C. Gordon, S.Dörre, P. Belardinelli, M. Stenroos, B. Zrenner, U. Ziemann and C. Zrenner Front. Hum. Neurosci. 15:691821

Sleep-dependent upscaled excitability and saturated neuroplasticity in the human brain: From brain physiology to cognition M. A. Salehinejad, E. Ghanavati, J. Reinders, J. G. Hengstler, M.-F. Kuo, M. A. Nitsche bioRxiv 2021.04.28.441823; doi: 

Voluntary motor commands are preferentially released during restricted sensorimotor beta rhythm phases S. J. Hussain, M. K. Vollmer, I. Iturrate, R. Quentin bioRxiv 776393; doi:

A set of electroencephalographic (EEG) data recorded during amplitude-modulated transcranial alternating current stimulation (AM-tACS) targeting 10-Hz steady-state visually evoked potentials (SSVEP) D. Haslacher, K. Nasr, S. E. Robinson, C. Braun, S. R. Soekadar Data in Brief 36 (2021) 107011

Decreased intersubject synchrony in dynamic valence ratings of sad movie contents in dysphoric individuals X. Li, Y. Zhu, E. Vuoriainen, C. Ye, P. Astikainen Scientific Reports (2021) 11:14419 

Cardiac Activity Impacts Cortical Motor Excitability E. Al, T. Stephani, M. Engelhardt, A. Villringer, V. Nikulin Research Square 2021

Phase-dependent offline enhancement of human motor memory S. J. Hussain, M. K. Vollmer, J. Stimely, G. Norato, C. Zrenner, U. Ziemann, E. R. Buch, L. G. Cohen BrainStimulation 14(4) 2021

Targeting motor cortex high-excitability states defined by functional connectivity with real-time EEG–TMS D. E. Vetter, C. Zrenner, P. Belardinelli, T. P. Mutanen, G. Kozák, L. Marzetti, U. Ziemann NeuroImage Volume 284, 2023

Bittium NeurOne can also be customized by combining it with other devices/modules. Here are the examples of additional accessories: Inclinometer Gonio- and Torsiometer Heart rate sensor Load cell, Force and Pressure sensors Accelerometer Gyro sensor GSR sensor EMG, ECG preamplifiers Customized modules and transducers